I graduated with a PhD in Microbiology from the Université de Bretagne Occidentale (France) in 2010. The research for my thesis was performed in the laboratory of Microbiology (MIC/LNR) of the French Research Institute for Exploitation of the Sea (IFREMER) under the supervision of Dr. Michèle Gourmelon. Following this, I gained two years of postdoctoral research experience as an experienced researcher in a Marie Curie ITN (Initial Training Network, SEACOAT project) in the laboratory of Prof. James Callow in the School of Biosciences, University of Birmingham (UK). I spent a further one year as a non permanent-assistant professor at the Université de Bretagne occidentale/University Laboratory of Biodiversity and Microbial Ecology (LUBEM) before joining the Tree/Microbe Interaction (IAM) laboratory (INRA Champenoux-Ecogenomics team) in September 2014 as an assistant professor.
During my PhD I developed four real-time PCR markers, targeting bacteria belonging to the Bacteroidales order, to discriminate and quantify human and animal (porcine or ruminant) faecal pollution in the environment (water and shellfish samples). I collected contaminated samples from various locations, and then applied newly developed host-associated markers in the environment at both the small and large scale. These analytical tools have now been transferred to French private water analysis laboratories.
My post-doctoral experience included studying the interactions between abiotic surfaces/bacterial biofilms and marine micro- and macro-algae. The effect of bacterial biofilms on the adhesion strength of algal cells had not been investigated before and the study culminated in a unique paper describing the importance of these interactions in relation to marine fouling–release coatings. I also reinforced my knowledge on the interactions between prokaryotic and eukaryotic organisms by studying the effects of metabolites secreted by the lactic acid bacteria Lactobacillus harbinensis on the physiological state of the yogurt spoilage yeast Yarrowia lipolytica.
My current research topic at the IAM Laboratory focuses on studying the interactions between bacteria and fungi during wood decomposition which is an important process in forest ecosystems (i.e. carbon and nutrient cycles). It is well known that saprotrophic basidiomycetes (mainly white-rot fungi) are the main wood decomposers in temperate forests, but little is known about the bacterial communities colonizing the wood or the interactions between these and the fungal communities and their overall effect on wood decomposition.
Publications:
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Yandi, W., S. Mieszkin, P. Martin-Tanchereau, ME. Callow, JA. Callow, L. Tyson, B. Liedberg and T. Ederth. 2014. Hydratation and chain entanglement determines the optimum thickness of Poly(HEMA-co-PEG10MA) brushes for effective resistance to settlement and adhesion of marine fouling organisms. ACS Appl Mater Interfaces, 23:6, 11448-58 |
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Yasani, B., D. E. Martinelli, G. Galli, S. Mieszkin, ME. Callow and JA. Callow. 2014. A comparison between different fouling release elastomer coatings containing surface-active polymers. Biofouling, 30:387-99 |
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Sterner, O., A. Serrano, S. Mieszkin, S. Zürcher, S. Tosatti, ME. Callow, JA. Callow and ND. Spencer. 2013. Photochemically prepared, two-component polymer-concentration gradients. Langmuir, 29:13031-13041 |
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Xiao, L., J. Li, S. Mieszkin, A. Di Fino, AS. Clare, ME. Callow, JA. Callow, M. Grunze, A. Rosenhahn and P. Levkin. 2013. Liquid-infused slippery surfaces show marine anti-biofouling properties. Applied Materials & Interfaces, 5:10074−10080 |
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Mieszkin, S., ME. Callow and JA. Callow. 2013. Interactions between bacterial biofilms and marine fouling algae: a mini-review. Biofouling, 29:1097-1113 |
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Serrano, A., O. Sterner, S. Mieszkin, S. Zürcher, S. Tosatti, ME. Callow, JA. Callow and ND. Spencer. 2013. Nonfouling response of hydrophilic uncharged polymers. Advanced Functional Materials, 23:5706-5718 |
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Raith, MR, CA. Kelty, JF. Griffith, A. Schriewer, S. Wuertz, S. Mieszkin, M. Gourmelon, GH. Reischer, AH. Farnleitner, JS. Ervin, PA. Holden, DL. Ebentier, JA. Jay, D Wang, AB. Boehm, T Gim Aw, JB. Rose, E. Balleste, WG. Meijer, M. Sivaganesan and OC. Shanks. 2013. Comparison of PCR and quantitative real-time PCR methods for the characterization of ruminant and cattle fecal pollution sources. Water Research, 47:6921-6928 |
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Mieszkin, S., MP. Caprais, C. Le Mennec, M. Legoff, TA Edge and M. Gourmelon. 2013. Identification of the origin of fecal contamination in estuarine oysters using Bacteroidales and F-specific RNA bacteriophage markers. Journal of Applied Microbiology, 115:897-907 |
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Mauffret, A., S. Mieszkin, M. Morizur, Y. Affiansah, S. Lozach and M. Gourmelon. 2013. Recent innovation in microbial source tracking using bacterial real-time quantitative PCR markers in shellfish. Marine Bulletin Pollution, 68(1-2):21-9 |
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Pranzetti, A., S. Mieszkin, P. Iqbal, FJ. Rawson, ME. Callow, JA. Callow, P. Koelsh, JA. Preece and PM. Mendes. 2013. Electrochemically controlled switching of charged surfaces for real-time control and regulation of bacterial adhesion. Advanced Materials, 25(15):2181-5 |
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Mieszkin, S., P Martin-Tanchereau, ME. Callow and JA. Callow.2012. Effect of bacterial biofilms formed on fouling-release coatings from natural seawater and Cobetia marina, on the adhesion strength of two marine algae. Biofouling, 28: 953-968 |
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Pranzetti, A., S. Salaün, S. Mieszkin, P. Iqbal, FJ. Rawson, ME. Callow, JA. Callow, P. Koelsh, JA. Preece and PM. Mendes. 2012. Electrochemically controlled switching of charged surfaces for real-time control and regulation of bacterial adhesion. Advanced Functional MaterialsDOI: 10.1002/adfm.201103067 |
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Marti,* R., S. Mieszkin*, O. Solecki, AM. Pourcher, D. Hervio-Heath, M. Gourmelon. 2011. Effects of oxygen and temperature on persistence of three pig-specific genetic markers and dynamics of two dominant pig manure populations in river water microcosms. Journal of Applied Microbiology, 111: 1159-1175* Contribution égale des auteurs |
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Jaffrezic, A., E. Jarde, AM. Pourcher, M. Gourmelon, MP. Caprais, D. Heddadj, P. Cottinet, M. Bilal, M. Derrien, R. Marti and S. Mieszkin. 2011. Microbial and chemical markers: runoff transfer in pig and cow manure-amended soils. Journal of Environmental Quality, 40: 959-968 |
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Gourmelon, M., MP. Caprais, S. Mieszkin, R. Marti, N. Wery, E. Jarde, M. Derrien, A. Jedas-Hecart, PY. Communal, A. Jaffrezic and AM. Pourcher. 2010. Development of microbial and chemical MST tools to identify the origin of the fecal pollution in bathing and shellfish harvesting waters in France. Water Research, 44: 4812-4824 |
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Gourmelon, M., MP. Caprais, C. Le Mennec, S. Mieszkin, C. Ponthoreau and M. Gendronneau. 2010. Application of library-independent Microbial Source Tracking methods for identifying the sources of faecal contamination in coastal areas. Water Science Technology, 61: 1401-1409 |
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Mieszkin, S., JF. Yala, R. Joubrel and M. Gourmelon. 2010. Phylogenetic analysis of Bacteroidales 16S rRNA gene sequences from human and animal effluents and assessment of ruminant faecal pollution by real-time PCR. Journal of Applied Microbiology, 108: 974-984 |
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Mieszkin, S., JP. Furet, G. Corthier and M. Gourmelon. 2009. Estimation of pig fecal contamination in a river catchment by real-time PCR using two pig-specific Bacteroidales 16S rRNA genetic markers. Applied and Environmental Microbiology, 75: 3045-3054 |
Main teaching activities (Université de Lorraine – Faculté des Sciences et Technologies de Nancy):
Years 1, 2 and 3:
-Microbiology (mycology and bacteriology)
-Environmental microbiology
-Plant physiology
-Cellular biology
Contact:
Sophie.mieszkin@univ-lorraine.fr
Faculté des Sciences et Technologies
Entrée 1B, 6ème étage
BP 239 – 54 506 Vandoeuvre les Nancy cedex – France
Tel: +33 3 83 68 42 35
Fax: +33 3 83 38 40 01
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Centre INRA Nancy Lorraine
54280 Champenoux – France
Tel : +33 3 83 39 40 88
Fax : +33 3 83 39 40 69
