|Gene Name: GSTUMT00010022001|
Length(AA) : 669
Localization : scaffold_65
Number of EST contigs matching the gene: 2
Number of ESTs : 5
|Nr Definition: hypothetical protein AN0236.2 |
Specie: [Aspergillus nidulans FGSC A4]
Accession: ref|XP_657840.1| Score: 270 E_value: 1e-21
|KEGG Definition: hypothetical protein|
Accession: ani:AN0236.2 Score: 270 E_value: 7e-22
|KOG Definition: Splicing factor 1/branch point binding protein (RRM superfamily) |
Classification: [RNA processing and modification].
Kog Number: KOG0119 Score: 244 E_value: 3e-21
|PFAM Definition: Atrophin-1, Atrophin-1 family. Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteristic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity..|
Pfam Number: pfam03154 Score: 279 E_value: 3e-25
|Swissprot: No Hit Found|
SignalP 3.0 predicts the presence and location of signal peptide cleavage sites in amino acid sequences.
The method incorporates a prediction of cleavage sites and a signal peptide/non-signal peptide prediction
based on a combination of several artificial neural networks and hidden Markov models.
|Smean score||Smean prediction||Smax score||Smax prediction||D-score||D prediction||HMM prediction|
TargetP 1.1 predicts the subcellular location of eukaryotic proteins. The location assignment is based on
the predicted presence of any of the N-terminal presequences: mitochondrial targeting peptide (mTP)
or secretory pathway signal peptide (SP).
|Mitochondrion Score||Secretory Score||Any other location||Localization||Reliability class||Predicted presenquence length|
Prediction of transmembrane helices in proteins
EST contigs matching with the Gene:
|Contig2689||No hit found|
|SY0AAB37YC14FM1||predicted protein [Ajellomyces capsulatus NAm1]||9e-07|