Tuber melanosporum DB

You are here: MycorWeb Genome resources Tuber melanosporum DB EST & Gene Sequences -> Contig card

Contig Name: SY0AAD57YC22FM1
Length(NT) : 598
Best Gene Model Blast : Link to GSTUMT00000574001 E-value : 0.0
Numbers of ESTs : 1

Blast Results:

Nr Definition: hypothetical protein An16g04260
Accession: ref|XP_001397737.1| Score: 169 E_value: 1e-10
KEGG Definition: hypothetical protein
Accession: ang:An16g04260 Score: 169 E_value: 6e-11
KOG Definition:
Classification: [RNA processing and modification, Transcription].
Kog Number: KOG0132 Score: 154 E_value: 2e-11
PFAM Definition: Atrophin-1, Atrophin-1 family. Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteristic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity..
Pfam Number: pfam03154 Score: 126 E_value: 3e-08

Sequence:
>SY0AAD57YC22FM1
TTGGAATTATCCCCTCAAATAAGACATTCCAGTTCCCACCCCACATACCT
CATATGGTGCCTACCTCACCATTACCTCATCATATTGCACCACCCCCAGG
AGTCCCACCGCCCGAGGGCTTCCCTATATCCCCCATTGGAGTCAACAATC
CCATGAACCCCTTCCTCCCCGGGCTTCAGCGAGGACCACCTTTCCCAAAT
GGAATGCCAATGTACTCTCCTGCCCAAATGCCGTTGAGTTCCGCCTCTCA
ATACCGTGGGTTCGCTGCGCCAAACGGTATGCAAATGCAAGTTCCAGCGA
CACCAGGCATGAGGCCACTTCCTCAGCAAGGGCGTGGCATTTTTGTGGCA
GAGATTGCTCCCGGAATGCCGCCTCAACTTTCTCCAGGGGTTCCATTAAT
TGCACCAGGGTCACCATTCATGAATAACCGTGCGGAACCTGTTCCCATAC
CAGGCAACCATTCCCACAACCGGGCGCTTTCTGGTTCCTTTGATCCAATC
CAACACCCGACGCCTATTCAACGACCCTCTAGCGTAGCCCCACCAAAGAG
CTTGGATGACAATCGCAATAGCATTGACGAGCTCTCCAAGGTAATGGG

Sequences in the Contig:

SY0AAD57YC22FM1