Tuber melanosporum DB

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Contig Name: Contig4567
Length(NT) : 1162
Best Gene Model Blast : Link to GSTUMT00011188001 E-value : 0.0
Numbers of ESTs : 3

Blast Results:

Nr Definition: hypothetical protein SS1G_14286
Accession: ref|XP_001584831.1| Score: 478 E_value: 6e-46
KEGG Definition: hypothetical protein
Accession: fgr:FG06833.1 Score: 451 E_value: 4e-43
KOG Definition:
Classification: [RNA processing and modification, Transcription].
Kog Number: KOG0132 Score: 153 E_value: 5e-11
PFAM Definition: Atrophin-1, Atrophin-1 family. Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteristic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity..
Pfam Number: pfam03154 Score: 155 E_value: 4e-11
Swissprot: O95696|BRD1_HUMAN
Gene Ontology:
GO:0005634 = Cellular component: nucleus

Sequence:
>Contig4567
TTGGCAAAGACCATGAAAATTGTTGAAGGCATCGGCACTATCCCTGTAGC
GAGGTGGTTACAAACCTGCAAGATTTGTGAGAGTACCGGGGGTGCTTGTG
TTGAGTGCCATGCGTGCCACGAGAGCGTTCATGTCGGTTGTGCACATAAG
GCGGGGTGGCGGATGGGATTTGATATCCAACCCGTGAAAGGCTCTAGGAG
AGACCAGATGAACATAATCAAGCTTGGCACTGAAACCGGAAGCATGACCG
CTGCTATCTGGTGTCCGGAGCATGAGCTGAAGACTACTTTACATGCGCTT
AACGAGATATCTGAGGAGACCGGACAGAATGCCTTGCAGCTATATACTAC
AACATATAAACAAGCGGATCTAACGCTTACGGGCACTGTTCGTAAGGCGA
ATCTAATGACAATTTCTACTAAGGCTTCGCAGTCGAACAGGAGAAATAGC
GCAGGGGGGGCATCCACGAATAGTATGGCTAATGGTAAAGAGTTGGCTTG
TTTGCCCACCACTGTGTACATCAAGACGGAAGGTGCAGAAGACAAAGTTG
GAGGAATCGAAGGGCTTCTCGATGATCACGTCGGAGGGGATGAGCCCAAG
CGCTGCTTCGAATGTCAAACGGATGTGAGCCCACTCTGGCGGAAGGTTCC
TATAGATGCACCAAGGCCAGCGGAGAACACTACACATCTGACCAATGGGA
CGCCACCTGATACTAATGGGATACTGGCCAATGGAGACGCGTCATCGCGT
TCGCGTACTGTTGGGCTACTCTGTCATCGTTGTCAAAACAAGGATCAGAC
GCCGGAACAGTCGCAGCATTCTCCCTCGTTTGCGGCAACGAACGGGAATC
AACGGAATAGATATGCGCCTCTTCCACCATTATCCACATTTTTGGCATCC
CAGCAGGCAGTCGCGCCACCCCCACCACCGCCTCCCGCTCCGCATCCCGT
GTTGATCCAGGGTGCCGGGCCATCTGGGGTACCGCAGCCAATGCCTCTCC
AGATAGCTCCCCAGTTAGTACCTCAAATGGCACCAATTCCTCAACACCAC
CCACACCCACAACAGCCCCAAGCGCTACCTCCTCACCCTCATCAGCAGGG
GCATGCACCCCCACCGAACCACATGCCTCCTCACCCGCCGCATATATCAC
CCCACCCCCCCC

Sequences in the Contig:

SY0AAC10YG04FM1 SY0AAC35YK19FM1 SY0AAD49YA05FM1