Tuber melanosporum DB

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Contig Name: Contig3755
Length(NT) : 1179
Best Gene Model Blast : Link to GSTUMT00010734001 E-value : 0.0
Numbers of ESTs : 3

Blast Results:

Nr Definition: hypothetical protein CHGG_08163
Accession: ref|XP_001225819.1| Score: 173 E_value: 1e-10
KEGG Definition: protein tyrosine phosphatase Pps1, putative
Accession: afm:AFUA_5G11690 Score: 148 E_value: 5e-08
KOG Definition:
Classification: [Intracellular trafficking, secretion, and vesicular transport].
Kog Number: KOG0307 Score: 111 E_value: 4e-06
PFAM Definition: Atrophin-1, Atrophin-1 family. Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteristic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity..
Pfam Number: pfam03154 Score: 117 E_value: 1e-06

Sequence:
>Contig3755
TTGGAACTCCTACTCCCGTTTCTCCTCCTCATAACGCCTCCCCCCCCCAA
CGAAAAAACTATTCATCGATTTTTTCTCAGTTGTGTGCATTGAATTGTTG
AAACCTCTGGATCAACCTGGGGGTGTGCTCGCTGACAGCAGCTCTACTCT
AACTGACCTGCGCTGCATTCCCGTCTCGGCCCTGGATACATATCCACACC
CATTCGATATTCCTACATATCATACCTTGCACACATACCCACTGTCCGCC
TCCATCTCCCTCCCTCACGCCAAAGGAGCACACCCGCCACTTTCACACTC
AACTACCCACCCTCCACCCTTCCTCTTTACCACACCAAGAACCCCACTCC
CTCATAATTCCCGTCTAAAAGCTGTATCGCCCAACGAATTCCGCTACATA
TCCCTTCCCTCCCTCCGCCACCTCACCCCGCTATTCCACCCCTACTGCCA
CGCCAAAGTTTTCCCTAAATTTCACACTTCGACACTTCCACCCACCTCCA
TCTATTCACCCAATACCATTCTGATATCCGTTCCTGCTGCTGCTGCTGCT
TTCACTGCAGCGCTCTACCCGATCCTCGGATCAATCAGACACAACATATT
GGGGCGTCATAACTTCCCGATTCGGTGTCAATCCTCCGACATTTGGTTTC
AAGGTAGTCGAGCAAGCCAGTCCGGGTAGCGTCACCAAGCATCGAGGTCT
GCATAACAAACTGAGAATCTCTTATCGACCATCCGCACTTTCCACTTTTC
CTCACAATCCTTCGCAATAGAAAGTGGTTGCCATGGCTGCCGTGGCCATT
CAACCTCCGAGGGACACTCCCACTCCTCCCCCAATGCCTACTACTACACC
AACCCCAACCCTACCGTTGCCCGGCGCCGCTTCCACCACCGCTCCCATCC
CGATTCCGAATAAGCACATGGCAGTATCTGGACCTGGGGCCCCCAACTAC
GGGAATCCAGTTACGCCCCCTGCTTCTCCTCATTCTGAGGAGTCGCATTC
GTCTGAAGAAGGAAATCGTTCTATGGCCTCTCTGCTATCCCCGGCGGAGA
GCTATCCTCTAATCTCGGAATCCCCACCCGTCCATACCATTGATGCTGCT
GGTGTAGCCGCCTCCCTTAACTATAGTTCGAGGCAAAGTTTACCGGACAT
TGAACAACTATTTCCCTGGGCCCATGGTC

Sequences in the Contig:

SY0AAB50YG23FM1 SY0AAC15YK17FM1 SY0AAD24YJ03FM1