Tuber melanosporum DB

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Contig Name: Contig1560
Length(NT) : 1288
Best Gene Model Blast : Link to GSTUMT00003267001 E-value : 0.0
Numbers of ESTs : 6

Blast Results:

Nr Definition: hypothetical protein SS1G_01106
Accession: ref|XP_001596914.1| Score: 707 E_value: 2e-72
KEGG Definition: hypothetical protein
Accession: fgr:FG03994.1 Score: 693 E_value: 4e-71
KOG Definition:
Classification: [General function prediction only].
Kog Number: KOG1944 Score: 300 E_value: 6e-28
PFAM Definition: Mpv17_PMP22, Mpv17 / PMP22 family. The 22-kDa peroxisomal membrane protein (PMP22) is a major component of peroxisomal membranes. PMP22 seems to be involved in pore forming activity and may contribute to the unspecific permeability of the organelle membrane. PMP22 is synthesised on free cytosolic ribosomes and then directed to the peroxisome membrane by specific targeting information. Mpv17 is a closely related peroxisomal protein. In mouse, the Mpv17 protein is involved in the development of early-onset glomerulosclerosis. More recently a homolog of Mpv17 in S. cerevisiae has been been found to be an integral membrane protein of the inner mitochondrial membrane where it has been proposed to have a role in ethanol metabolism and tolerance during heat-shock. Defects in MPV17 is associated with mitochondrial DNA depletion syndrome (MDDS) and Navajo neurohepatopathy (NNH). MDDS is a clinically heterogeneous group of disorders characterised by a reduction in mitochondrial DNA (mtDNA) copy number. Primary mtDNA depletion is inherited as an autosomal recessive trait and may affect single organs, typically muscle or liver, or multiple tissues. Individuals with the hepatocerebral form of mitochondrial DNA depletion syndrome have early progressive liver failure and neurologic abnormalities, hypoglycemia, and increased lactate in body fluids. NNH is an autosomal recessive disease that is prevalent among Navajo children in the South Western states of America. The major clinical features are hepatopathy, peripheral neuropathy, corneal anesthesia and scarring, acral mutilation, cerebral leukoencephalopathy, failure to thrive, and recurrent metabolic acidosis with intercurrent infections. Infantile, childhood, and classic forms of NNH have been described. Mitochondrial DNA depletion was detected in the livers of patients, suggesting a primary defect in mtDNA maintenance..
Pfam Number: pfam04117 Score: 155 E_value: 4e-11
Swissprot: O14142|SYM1_SCHPO
Gene Ontology:
GO:0005739 = Cellular component: mitochondrion

Sequence:
>Contig1560
TTGGCATCCATCCCCCATCTCATCATCGTTAGACCCCGCTCCCAGCTTCC
AACCTCAGCCTTAGCCAGTACCCACGCGTACTCAGCGTCAAACTTACTGC
CGCCCGATACTGATACCGGTACCGCACCGTAGTGGTAACCTTATTGTCGC
TTCCCCTCATCGAACCTCCTTCATCCTCCTCCCCCATCAAACGCCACCCA
TACTCTTGCCTTCCCATCCCTTAGACCTTCCTCAACCCCTCGTCAAACGT
GAAGACAGCCCTTCACTTTTCTTCTTCATCAAAATGGCATCGTCGGACCG
CCTTCGTTTGATCCGTTCTGCACGAAATTACCATCTTTGTGGCCGCGTGC
CTTTGGTCAACGTTGTTGTGCTCTTTATCGAGATCGTGGGATTAGCTCGT
GTGGCTATGCAATATGACCTACATTTTGGCTCCAAGCCAATACTGACCAT
GATGATTACCAACTCGTTGCTGAACGGGGTGGCAGATACCATCGCCCAAA
CAGTCACCTCCATACGAGCTAAAACCCGCAGACCTCGAGATTTTGGAAAG
AAGGATAGCATTTCAATAGAAATCCATGAGTTGAATGAGAAGGGCCCTTT
ACCTACCCATCGAGCGGAACTCTTGGCCACCTCACCGCCGCCCTTTGACT
TTGAGCGGCTGGTGAGATACATGGCATGGGGTTTCCTTATTGCGCCTCTG
CTATTCAAGTGGTTCGGCTTTCTCTCGGATACCTTCCCCATTACACCAAC
CAGCGGAATCGCACCGGCCCTCTGGCGTGTAGCTATTGACCAGCTCATCC
TCTCTCCTACCTCCCTTGCGGTCTTCTTCATCTACATGACCTTAGCAGAG
GGAGGTGGAAAGAAAGCTATCATTCGAAAATTCGATATGGTTTATATTTC
CGCTTTGAAATCCAATTATATTCTATGGCCAGCTGTTCAAATACTAAACT
TCCGAGTTGTTCCTCTTTCACTCCAACTGCCTTTTGCCTCGACCGTTGGA
ATCGCATGGACAGTGTACCTTTCGCTCACAAACGACGCCGCAGATTAATG
GCCAGTTGTAGATCTCTGCTTCAATCTCAGTAGACCCAGCCCGAACACCT
CCCTAAAACAGTCTAATACCAATCAGATCTCTCAAGTCCGGCTCTCACGG
TTGGTAGACTATCAAAAAAAAAAAAAAGCCTCTGCTCTCTTTCCATTTTC
ACCGTTTTCACCTTCTACGCTTTCCACTCTCTCTCGGCCAAATTACTCGC
GTATATGGTGGGATAAAGATAGGGTAATAAGGTCAACG

Sequences in the Contig:

SY0AAA39YJ20FM1 SY0AAA54YN22FM1 SY0AAB13YA23FM1
SY0AAB19YI07FM1 SY0AAB32YM07FM1 SY0AAC25YO01FM1