Welcome to INRA HeterobasionDB, the Heterobasidion genome database Version 1.0.
Heterobasidion annosum s.l., a white-rot fungus, causes a devastating root rot in conifer plantations and natural forests throughout the Northern Hemisphere. Mating tests, morphological, and molecular phylogeny studies have revealed a separation of five operative taxonomic units (Intersterility IS groups) within the species complex, North American P, North American S, European P, European S, and European F, with partly overlapping geographic distributions and host preferences.
The genome sequencing for H. annosum provides the first comprehensive genetic information on a plant pathogenic homobasidiomycete allowing for new insights into plant-microbe interactions with trees, in particular conifers. It is important to broaden the taxonomic base for understanding the mechanisms of plant-microbe interactions, studying genes and proteins involved, and identifying pathogenicity determinants. Comparative genomics of plant pathogens with a gradient of taxonomic relatedness to H. annosum will help to understand the evolution of such factors.
Genetic control with durable resistance line of tree material is the choice for sustainable forestry, however genetic control requires in depth knowledge of infection process and detailed information on the molecular mechanism involved.